The best dua is asking for afiyah (well-being)
A man came to the Prophet ﷺ and said: O Messenger of Allah, which supplication is best? He said: "Ask your Lord for well-being and protection in this world and the Hereafter."
Then he came to him on the second day and said: O Messenger of Allah, which supplication is best? He said the same to him. Then he came to him on the third day, and he said the same to him. He said: "If you are given well-being in this world and are given it in the Hereafter, then you have succeeded."
أَنَّ رَجُلاً جَاءَ إِلَى النَّبِيِّ ﷺ، فَقَالَ: يَا رَسُولَ اللَّهِ، أَىُّ الدُّعَاءِ أَفْضَلُ؟ قَالَ: «سَلْ رَبَّكَ الْعَافِيَةَ وَالْمُعَافَاةَ فِي الدُّنْيَا وَالآخِرَةِ».
ثُمَّ أَتَاهُ فِي الْيَوْمِ الثَّانِي، فَقَالَ: يَا رَسُولَ اللَّهِ، أَىُّ الدُّعَاءِ أَفْضَلُ؟ فَقَالَ لَهُ مِثْلَ ذَلِكَ. ثُمَّ أَتَاهُ فِي الْيَوْمِ الثَّالِثِ، فَقَالَ لَهُ مِثْلَ ذَلِكَ، قَالَ: «فَإِذَا أُعْطِيتَ الْعَافِيَةَ فِي الدُّنْيَا، وَأُعْطِيتَهَا فِي الآخِرَةِ، فَقَدْ أَفْلَحْتَ».
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