'A'isha reported, I did not see anyone else being afflicted with more severe illness than Messenger of Allah ﷺ. In the narration transmitted by 'Uthman there is a slight variation of wording.  

عَائِشَةُ مَا رَأَيْتُ رَجُلاً أَشَدَّ عَلَيْهِ الْوَجَعُ مِنْ رَسُولِ اللَّهِ ﷺ وَفِي رِوَايَةِ عُثْمَانَ مَكَانَ الْوَجَعِ وَجَعًا  

This hadith has been narrated on the authority of A'mash through other chains of transmitters.  

عَنِ الأَعْمَشِ بِإِسْنَادِ جَرِيرٍ مِثْلَ حَدِيثِهِ  

I visited Messenger of Allah ﷺ as he was running a high temperature. I touched his body with my hand and said to him: Messenger of Allah, you are running a high temperature, whereupon Messenger of Allah ﷺ said: Yes, it is so. I comparatively have a more severe fever than any one of you. I said: Is it because there is a double reward in store for you? Thereupon Messenger of Allah ﷺ said: Yes, it is so. And Messenger of Allah ﷺ again said: When a Muslim falls ill, his compensation is that his minor sins are obliterated just as leaves fall (in autumn). In the hadith transmitted on the authority of Zubair there is (no mention of these words):" I touched his body with my hands."  

دَخَلْتُ عَلَى رَسُولِ اللَّهِ ﷺ وَهُوَ يُوعَكُ فَمَسِسْتُهُ بِيَدِي فَقُلْتُ يَا رَسُولَ اللَّهِ إِنَّكَ لَتُوعَكُ وَعْكًا شَدِيدًا فَقَالَ رَسُولُ اللَّهِ ﷺ أَجَلْ إِنِّي أُوعَكُ كَمَا يُوعَكُ رَجُلاَنِ مِنْكُمْ قَالَ فَقُلْتُ ذَلِكَ أَنَّ لَكَ أَجْرَيْنِ فَقَالَ رَسُولُ اللَّهِ ﷺ أَجَلْ ثُمَّ قَالَ رَسُولُ اللَّهِ ﷺ مَا مِنْ مُسْلِمٍ يُصِيبُهُ أَذًى مِنْ مَرَضٍ فَمَا سِوَاهُ إِلاَّ حَطَّ اللَّهُ بِهِ سَيِّئَاتِهِ كَمَا تَحُطُّ الشَّجَرَةُ وَرَقَهَا  

He said: Yes, by Him in Whose Hand is my life, there is no Muslim upon the earth." The rest of the hadith is the same.  

عَنِ الأَعْمَشِ بِإِسْنَادِ جَرِيرٍ نَحْوَ حَدِيثِهِ وَزَادَ فِي حَدِيثِ أَبِي مُعَاوِيَةَ قَالَ نَعَمْ وَالَّذِي نَفْسِي بِيَدِهِ مَا عَلَى الأَرْضِ مُسْلِمٌ  

What makes you laugh? They said: Such and such person stumbled against the rope of the tent and he was about to break his neck or lose his eyes. She said: Don't laugh for I heard Messenger of Allah ﷺ as saying: If a Muslim runs a thorn or (gets into trouble) severe than this, there is assured for him (a higher) rank and his sins are obliterated.  

دَخَلَ شَبَابٌ مِنْ قُرَيْشٍ عَلَى عَائِشَةَ وَهِيَ بِمِنًى وَهُمْ يَضْحَكُونَ فَقَالَتْ مَا يُضْحِكُكُمْ قَالُوا فُلاَنٌ خَرَّ عَلَى طُنُبِ فُسْطَاطٍ فَكَادَتْ عُنُقُهُ أَوْ عَيْنُهُ أَنْ تَذْهَبَ فَقَالَتْ لاَ تَضْحَكُوا فَإِنِّي سَمِعْتُ رَسُولَ اللَّهِ ﷺ قَالَ مَا مِنْ مُسْلِمٍ يُشَاكُ شَوْكَةً فَمَا فَوْقَهَا إِلاَّ كُتِبَتْ لَهُ بِهَا دَرَجَةٌ وَمُحِيَتْ عَنْهُ بِهَا خَطِيئَةٌ  

A believer does not receive (the trouble) of running a thorn or more than that but Allah elevates him in rank or effaces his sins because of that.  

قَالَ رَسُولُ اللَّهِ ﷺ مَا يُصِيبُ الْمُؤْمِنَ مِنْ شَوْكَةٍ فَمَا فَوْقَهَا إِلاَّ رَفَعَهُ اللَّهُ بِهَا دَرَجَةً أَوْ حَطَّ عَنْهُ بِهَا خَطِيئَةً  

A believer does not undergo (the trouble) of running a thorn or more than that when Allah effaces his sins.  

قَالَ رَسُولُ اللَّهِ ﷺ لاَ تُصِيبُ الْمُؤْمِنَ شَوْكَةٌ فَمَا فَوْقَهَا إِلاَّ قَصَّ اللَّهُ بِهَا مِنْ خَطِيئَتِهِ  

The above hadith has been transmitted by Hisham with the same chain.  

حَدَّثَنَا هِشَامٌ بِهَذَا الإِسْنَادِ  

Messenger of Allah ﷺ said: There is no trouble that comes to a believer except that it obliterates from his sins, even if it is the pricking of a thorn  

أَنَّ رَسُولَ اللَّهِ ﷺ قَالَ مَا مِنْ مُصِيبَةٍ يُصَابُ بِهَا الْمُسْلِمُ إِلاَّ كُفِّرَ بِهَا عَنْهُ حَتَّى الشَّوْكَةِ يُشَاكُهَا  

No trouble comes to a believer even if it is the pricking of a thorn that it becomes (the means) whereby his sins are effaced or his sins are obliterated. Yazid says: He does not know which word 'Urwa said (whether he said Qussa or Kuffira).  

عَنْ عَائِشَةَ زَوْجِ النَّبِيِّ ﷺ أَنَّ رَسُولَ اللَّهِ ﷺ قَالَ لاَ يُصِيبُ الْمُؤْمِنَ مِنْ مُصِيبَةٍ حَتَّى الشَّوْكَةِ إِلاَّ قُصَّ بِهَا مِنْ خَطَايَاهُ أَوْ كُفِّرَ بِهَا مِنْ خَطَايَاهُ لاَ يَدْرِي يَزِيدُ أَيَّتُهُمَا قَالَ عُرْوَةُ  

I heard Messenger of Allah ﷺ as saying: There is nothing (in the form of trouble) that comes to a believer even if it is the pricking of a thorn that there is decreed for him by Allah good or his sins are obliterated.  

سَمِعْتُ رَسُولَ اللَّهِ ﷺ يَقُولُ مَا مِنْ شَىْءٍ يُصِيبُ الْمُؤْمِنَ حَتَّى الشَّوْكَةِ تُصِيبُهُ إِلاَّ كَتَبَ اللَّهُ لَهُ بِهَا حَسَنَةً أَوْ حُطَّتْ عَنْهُ بِهَا خَطِيئَةٌ  

Never a believer is stricken with discomfort, hardship or illness, grief or even with mental worry that his sins are not expiated for him.  

عَنْ أَبِي سَعِيدٍ وَأَبِي هُرَيْرَةَ أَنَّهُمَا سَمِعَا رَسُولَ اللَّهِ ﷺ يَقُولُ مَا يُصِيبُ الْمُؤْمِنَ مِنْ وَصَبٍ وَلاَ نَصَبٍ وَلاَ سَقَمٍ وَلاَ حَزَنٍ حَتَّى الْهَمِّ يُهَمُّهُ إِلاَّ كُفِّرَ بِهِ مِنْ سَيِّئَاتِهِ  

"Whoever does evil will be requited for it", and when this was conveyed to the Muslims they were greatly perturbed. Thereupon Messenger of Allah ﷺ said: Be moderate and stand firm in trouble that falls to the lot of a Muslim (as that) is an expiation for him; even stumbling on the path or the pricking of a thorn (are an expiation for him). Muslim said that 'Umar b. Abd al-Rahman Muhaisin was from amongst the people of Mecca.  

لَمَّا نَزَلَتْ { مَنْ يَعْمَلْ سُوءًا يُجْزَ بِهِ} بَلَغَتْ مِنَ الْمُسْلِمِينَ مَبْلَغًا شَدِيدًا فَقَالَ رَسُولُ اللَّهِ ﷺ قَارِبُوا وَسَدِّدُوا فَفِي كُلِّ مَا يُصَابُ بِهِ الْمُسْلِمُ كَفَّارَةٌ حَتَّى النَّكْبَةِ يُنْكَبُهَا أَوِ الشَّوْكَةِ يُشَاكُهَا قَالَ مُسْلِمٌ هُوَ عُمَرُ بْنُ عَبْدِ الرَّحْمَنِ بْنِ مُحَيْصِنٍ مِنْ أَهْلِ مَكَّةَ  

Umm Sa'ib or Umm Musayyib. why is it that you are shivering? She said:" It is fever and may it not be blessed by Allah, whereupon he (the Holy Prophet) said: Don't curse fever for it expiates the sin of the children of Adam just as furnace removes the alloy of iron.  

أَنَّ رَسُولَ اللَّهِ ﷺ دَخَلَ عَلَى أُمِّ السَّائِبِ أَوْ أُمِّ الْمُسَيَّبِ فَقَالَ مَا لَكِ يَا أُمَّ السَّائِبِ أَوْ يَا أُمَّ الْمُسَيَّبِ تُزَفْزِفِينَ قَالَتِ الْحُمَّى لاَ بَارَكَ اللَّهُ فِيهَا فَقَالَ لاَ تَسُبِّي الْحُمَّى فَإِنَّهَا تُذْهِبُ خَطَايَا بَنِي آدَمَ كَمَا يُذْهِبُ الْكِيرُ خَبَثَ الْحَدِيدِ  

Ibn Abbas said to me: May I show you a woman of Paradise? I said: Yes. He said: Here is this dark-complexioned woman. She came to Allah's Apostle ﷺ and said: I am suffering from falling sickness and I become naked; supplicate Allah for me, whereupon he (the Holy Prophet) said: Show endurance as you can do and there would be Paradise for you and, if you desire, I supplicate Allah that He may cure you. She said: I am prepared to show endurance (but the unbearable trouble is) that I become naked, so supplicate Allah that He should not let me become naked, so he supplicated for her.  

هَذِهِ الْمَرْأَةُ السَّوْدَاءُ أَتَتِ النَّبِيَّ ﷺ قَالَتْ إِنِّي أُصْرَعُ وَإِنِّي أَتَكَشَّفُ فَادْعُ اللَّهَ لِي قَالَ إِنْ شِئْتِ صَبَرْتِ وَلَكِ الْجَنَّةُ وَإِنْ شِئْتِ دَعَوْتُ اللَّهَ أَنْ يُعَافِيَكِ قَالَتْ أَصْبِرُ قَالَتْ فَإِنِّي أَتَكَشَّفُ فَادْعُ اللَّهَ أَنْ لاَ أَتَكَشَّفَ فَدَعَا لَهَا