The Prophet ﷺ stood up and delivered a sermon, and pointing to ʿAisha's house (i.e. eastwards), he said thrice, "Affliction (will appear from) here," and, "from where the side of the Satan's head comes out (i.e. from the East).
قَامَ النَّبِيُّ ﷺ خَطِيبًا فَأَشَارَ نَحْوَ مَسْكَنِ عَائِشَةَ فَقَالَ هُنَا الْفِتْنَةُ ثَلاَثًا مِنْ حَيْثُ يَطْلُعُ قَرْنُ الشَّيْطَانِ